产品货号：
Z16303
中文名称：
DDR1抗体
英文名称：
Anti-DDR1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 组分 | 50μL | 100μL | 150μL | 保存 |
| DDR1抗体 | 50μL | 100μL | 150μL | -20℃ |
| WB抗体稀释液 | 5mL | 5mL | 5mL | 4℃ |
| IH抗体稀释液 | 5mL | 5mL | 5mL | 4℃ |
保存：-20℃，有效期1年，避免反复冻融，4℃可保存6个月。
| 抗体名称 | Anti-DDR1 Antibody |
| 指标别名 | CAK;CD167;Cell adhesion kinase;DDR;DDR1;EDDR1;HGK2;Mammary carcinoma kinase 10;MCK 10;MCK10;NEP;NTRK4;Protein tyrosine kinase 3A;Protein tyrosine kinase RTK 6;PTK3;PTK3A;RTK6;TRK E;TRKE;Tyrosine kinase DDR;Tyrosine protein kinase CAK |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM,ICC/IF,ELISA |
| 基因名称 | DDR1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human MCK10/NEP/DDR1 recombinant protein (Position:R341-A909). |
| 实际分子量 | 100～140KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | DDR1(Discoidin domain receptor family,member 1) also known as NEP,EDDR1,NTRK4,TRKE,DDR,CAK or RTK6,is a human gene.The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen.This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain.The DDR1 gene is mapped on 6p21.33.The fibrillar collagens and immobilized collagen activated DDR1 receptor phosphorylation after prolonged treatment.Bhatt et al.(2000) showed that Ddr1 was highly expressed in the cerebellum of developing and adult mouse brain,and that both Ddr1 and collagen IV were highly expressed in the pial layer of the cerebellar cortex.°Cocultures of collagen I- and IV-expressing mouse pial cells with Ddr1-expressing granule cells resulted in granule cell neurite extension.Inhibition of collagen-Ddr1signaling reduced granule cell neurite elongation. |
| Uniprot ID | Q08345 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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